SAMe (S-adenosylmethionine) is a compound found in the body. S-Adenosyl Methionine (SAMe) is derived from the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAMe is also required for the biosynthesis of critical neurotransmitters and hormones.

Function of SAMe in the body

SAMe is involved in numerous biochemical reactions in tissues including the liver, joints and brain. Some of the critical roles it performs in biochemical reactions are:

  • Enhances Mood & Neural Function: SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.
  • Promotes Joint Comfort & Mobility: SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.
  • Supports Liver Health & Detoxification: SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.